The Medicine Shoppe franchise: cost, fees and total investment
Short answer: The The Medicine Shoppe franchise fee is $0 and the total initial investment ranges from $130,000 to $894,876, with about $65,000 in liquid cash required, based on franchise disclosure data compiled in October 2026. Confirm current figures in Items 5 and 7 of the The Medicine Shoppe FDD.
What are the The Medicine Shoppe franchise fees and investment?
The The Medicine Shoppe franchise requires a franchise fee of $0 and a total initial investment of $130,000 to $894,876. The franchise fee is one line inside the total investment, which also covers location, equipment, opening inventory and working capital.
| Franchise fee (FDD Item 5) | $0 |
|---|---|
| Total initial investment (FDD Item 7) | $130,000 to $894,876 |
| Minimum liquid cash | $65,000 |
| US locations | 292 |
| Industry | Retail (Pharmacy) |
| Headquarters | Dublin, Ohio |
| Founded | 1970 |
| Franchising since | 1970 |
How does the The Medicine Shoppe investment compare with other retail franchises?
The Medicine Shoppe's minimum investment of $130,000 is at or below the median minimum investment of $159,700 across the 223 retail franchises in the SelectFranchiseList database. 132 of the other 222 brands in this industry start at a higher investment. Its franchise fee starting at $0 compares with an industry median of $30,000.
By minimum investment, The Medicine Shoppe belongs with franchises from $100,000 to $250,000.
What should you verify in the The Medicine Shoppe FDD?
Verify six parts of the The Medicine Shoppe Franchise Disclosure Document before you sign, because figures change with every annual FDD:
- Item 5 and Item 6: the current franchise fee, royalty, marketing fund and technology fees.
- Item 7: the full investment range by expense line, including working capital.
- Item 19: whether The Medicine Shoppe discloses financial performance data, and which units it covers.
- Item 20: openings, closures and transfers, plus contacts for current and former franchisees.
- Item 21: the franchisor's audited financial statements.
- Item 12: whether your territory is protected.
The full list of Items is in the FDD guide. You must receive the FDD at least 14 calendar days before you sign a binding agreement or pay any money.
Which franchises are similar to The Medicine Shoppe?
These retail franchises have the closest minimum investment to The Medicine Shoppe:
| Franchise | Franchise fee | Total investment |
|---|---|---|
| Medicap Pharmacy | $0 | $130,000 to $894,876 |
| Little Nest Portraits | $40,000 | $130,500 to $270,000 |
| Nutrition By Max Muscle | $35,000 | $129,000 to $283,500 |
| PayMore | $35,000 | $131,750 to $256,500 |
| Digital Doc | $44,900 | $128,200 to $195,500 |
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Frequently asked questions
How much does a The Medicine Shoppe franchise cost?
The total initial investment for a The Medicine Shoppe franchise ranges from $130,000 to $894,876, including a franchise fee of $0, according to franchise disclosure data compiled in October 2026. The exact amount depends on location, build-out and working capital, as shown in Item 7 of the FDD.
How much cash do you need to open a The Medicine Shoppe franchise?
The Medicine Shoppe lists a minimum of about $65,000 in liquid cash. Lenders usually finance part of the remaining investment, and the franchisor confirms its capital requirements during qualification.
How many The Medicine Shoppe locations are there?
The Medicine Shoppe reported 292 US locations in the data compiled in October 2026. Item 20 of the FDD shows openings, closures and transfers for the last three years.
How long has The Medicine Shoppe been franchising?
The Medicine Shoppe started offering franchises in 1970 after the company was founded in 1970.
Figures are compiled from franchise disclosure data and public franchise listings as of October 2026 and may have changed. The Medicine Shoppe and its trademarks belong to their owner; SelectFranchiseList is not affiliated with or endorsed by The Medicine Shoppe. This page is not an offer to sell a franchise. Only the franchisor's current FDD is authoritative.